Paul J. Manberg, Ph.D.


1. Association Between First-Line Immune Checkpoint Inhibition and Survival for Medicare-Insured Patients With Advanced Non-Small Cell Lung Cancer.  Kehl KL, Greenwald S, Chamoun NG, Manberg PJ, Schrag D. JAMA Netw Open. 2021 May 3;4(5):e2111113. doi: 10.1001/jamanetworkopen.2021.11113. PMID: 34019086 Free PMC article.
2. Efficacy and Safety of Low-field Synchronized Transcranial Magnetic Stimulation (sTMS) for Treatment of Major Depression.  Leuchter AF, Cook IA, Feifel D, Goethe JW, Husain M, Carpenter LL, Thase ME, Krystal AD, Philip NS, Bhati MT, Burke WJ, Howland RH, Sheline YI, Aaronson ST, Iosifescu DV, O’Reardon JP, Gilmer WS, Jain R, Burgoyne KS, Phillips B, Manberg PJ, Massaro J, Hunter AM, Lisanby SH, George MS. Brain Stimul. 2015 Jul-Aug;8(4):787-94. doi: 10.1016/j.brs.2015.05.005. Epub 2015 May 22. PMID: 26143022 Clinical Trial.
3. A prospective evaluation of the incidence of adverse events in nurse-administered moderate sedation guided by sedation scores or Bispectral Index.  Yang KS, Habib AS, Lu M, Branch MS, Muir H, Manberg P, Sigl JC, Gan TJ. Anesth Analg. 2014 Jul;119(1):43-48. doi: 10.1213/ANE.0b013e3182a125c3. PMID: 24413547
4. Hospital stay and mortality are increased in patients having a “triple low” of low blood pressure, low bispectral index, and low minimum alveolar concentration of volatile anesthesia.  Sessler DI, Sigl JC, Kelley SD, Chamoun NG, Manberg PJ, Saager L, Kurz A, Greenwald S. Anesthesiology. 2012 Jun;116(6):1195-203. doi: 10.1097/ALN.0b013e31825683dc. PMID: 22546967
5. Broadly applicable risk stratification system for predicting duration of hospitalization and mortality.  Sessler DI, Sigl JC, Manberg PJ, Kelley SD, Schubert A, Chamoun NG. Anesthesiology. 2010 Nov;113(5):1026-37. doi: 10.1097/ALN.0b013e3181f79a8d. PMID: 20966661
6. Anesthesia awareness and the bispectral index.  Kelley SD, Manberg PJ, Sigl JC. N Engl J Med. 2008 Jul 24;359(4):427-8; author reply 430-1. doi: 10.1056/NEJMc086136. PMID: 18650522 No abstract available.
7. Regulatory challenges facing closed-loop anesthetic drug infusion devices.  Manberg PJ, Vozella CM, Kelley SD. Clin Pharmacol Ther. 2008 Jul;84(1):166-9. doi: 10.1038/clpt.2008.79. Epub 2008 May 7. PMID: 18463624 Review.
8. Bispectral index monitoring.  Rosow C, Manberg PJ. Anesthesiol Clin North Am. 2001 Dec;19(4):947-66, xi. doi: 10.1016/s0889-8537(01)80018-3. PMID: 11778388 Review.
9. Computer simulation to determine how rapid anesthetic recovery protocols to decrease the time for emergence or increase the phase I postanesthesia care unit bypass rate affect staffing of an ambulatory surgery center.  Dexter F, Macario A, Manberg PJ, Lubarsky DA. Anesth Analg. 1999 May;88(5):1053-63. doi: 10.1097/00000539-199905000-00016. PMID: 10320168
10. Bispectral index monitoring allows faster emergence and improved recovery from propofol, alfentanil, and nitrous oxide anesthesia. BIS Utility Study Group.  Gan TJ, Glass PS, Windsor A, Payne F, Rosow C, Sebel P, Manberg P. Anesthesiology. 1997 Oct;87(4):808-15. doi: 10.1097/00000542-199710000-00014. PMID: 9357882 Clinical Trial.
11. Bispectral analysis measures sedation and memory effects of propofol, midazolam, isoflurane, and alfentanil in healthy volunteers.  Glass PS, Bloom M, Kearse L, Rosow C, Sebel P, Manberg P. Anesthesiology. 1997 Apr;86(4):836-47. doi: 10.1097/00000542-199704000-00014. PMID: 9105228
12. A multicenter study of bispectral electroencephalogram analysis for monitoring anesthetic effect.  Sebel PS, Lang E, Rampil IJ, White PF, Cork R, Jopling M, Smith NT, Glass PS, Manberg P. Anesth Analg. 1997 Apr;84(4):891-9. doi: 10.1097/00000539-199704000-00035. PMID: 9085977 Clinical Trial.
13. Prediction of movement using bispectral electroencephalographic analysis during propofol/alfentanil or isoflurane/alfentanil anesthesia.  Vernon JM, Lang E, Sebel PS, Manberg P. Anesth Analg. 1995 Apr;80(4):780-5. doi: 10.1097/00000539-199504000-00023. PMID: 7893035 Clinical Trial.
14. Bispectral analysis of the electroencephalogram correlates with patient movement to skin incision during propofol/nitrous oxide anesthesia.  Kearse LA Jr, Manberg P, Chamoun N, deBros F, Zaslavsky A. Anesthesiology. 1994 Dec;81(6):1365-70. doi: 10.1097/00000542-199412000-00010. PMID: 7992904 Clinical Trial.
15. Bispectral analysis of the electroencephalogram during induction of anesthesia may predict hemodynamic responses to laryngoscopy and intubation.  Kearse LA Jr, Manberg P, DeBros F, Chamoun N, Sinai V. Electroencephalogr Clin Neurophysiol. 1994 Mar;90(3):194-200. doi: 10.1016/0013-4694(94)90091-4. PMID: 7511501 Clinical Trial.
16. Neurotensin-like immunoreactivity in cerebrospinal fluid of patients with schizophrenia, depression, anorexia nervosa-bulimia, and premenstrual syndrome.  Nemeroff CB, Bissette G, Widerlov E, Beckmann H, Gerner R, Manberg PJ, Lindstrom L, Prange AJ Jr, Gattaz WF. J Neuropsychiatry Clin Neurosci. 1989 Winter;1(1):16-20. doi: 10.1176/jnp.1.1.16. PMID: 2577718
17. Isoelectrofocusing profiles of human urinary LH and FSH.  Manberg PJ. Fertil Steril. 1987 Aug;48(2):342-3. doi: 10.1016/s0015-0282(16)59372-8. PMID: 3111895 No abstract available.
18. Single-dose pharmacokinetics of clomiphene citrate in normal volunteers.  Mikkelson TJ, Kroboth PD, Cameron WJ, Dittert LW, Chungi V, Manberg PJ. Fertil Steril. 1986 Sep;46(3):392-6. doi: 10.1016/s0015-0282(16)49574-9. PMID: 3091405 Clinical Trial.
19. Problems in the development of neuropeptides as psychotherapeutic drugs.  Manberg PJ. Prog Clin Biol Res. 1985;192:343-8. PMID: 4080714
20. Neuropeptides in CSF and post-mortem brain tissue of normal controls, schizophrenics and Huntington’s choreics.  Manberg PJ, Nemeroff CB, Bissette G, Widerlov E, Youngblood WW, Kizer JS, Prange AJ Jr. Prog Neuropsychopharmacol Biol Psychiatry. 1985;9(1):97-108. doi: 10.1016/0278-5846(85)90184-8. PMID: 2859637
21. Bupropion in the treatment of psychotic depression: two case reports.  Manberg PJ, Carter RG. J Clin Psychiatry. 1984 May;45(5):230-1. PMID: 6427198
22. Regional brain concentrations of neuropeptides in Huntington’s chorea and schizophrenia.  Nemeroff CB, Youngblood WW, Manberg PJ, Prange AJ Jr, Kizer JS. Science. 1983 Sep 2;221(4614):972-5. doi: 10.1126/science.6136092. PMID: 6136092
23. Overview of clinically significant adverse reactions to bupropion.  Van Wyck Fleet J, Manberg PJ, Miller LL, Harto-Truax N, Sato T, Fleck RJ, Stern WC, Cato AE. J Clin Psychiatry. 1983 May;44(5 Pt 2):191-6. PMID: 6406456 Clinical Trial.
24. A double-blind comparison of bupropion and amitriptyline in depressed inpatients.  Davidson J, Miller R, Van Wyck Fleet J, Strickland R, Manberg P, Allen S, Parrott R. J Clin Psychiatry. 1983 May;44(5 Pt 2):115-7. PMID: 6406438 Clinical Trial.
25. Subnormal CSF levels of neurotensin in a subgroup of schizophrenic patients: normalization after neuroleptic treatment.  Widerlöv E, Lindström LH, Besev G, Manberg PJ, Nemeroff CB, Breese GR, Kizer JS, Prange AJ Jr. Am J Psychiatry. 1982 Sep;139(9):1122-6. doi: 10.1176/ajp.139.9.1122. PMID: 6126127 No abstract available.
26. Development of a radioimmunoassay for Pro-Leu-Gly-NH2 (PLG or MIF-I): evidence that PLG is not present in rat brain.  Manberg PJ, Youngblood WW, Kizer JS. Brain Res. 1982 Jun 10;241(2):279-84. doi: 10.1016/0006-8993(82)91064-2. PMID: 6125241
27. Regional distribution of neurotensin in human brain.  Manberg PJ, Youngblood WW, Nemeroff CB, Rossor MN, Iversen LL, Prange AJ Jr, Kizer JS. J Neurochem. 1982 Jun;38(6):1777-80. doi: 10.1111/j.1471-4159.1982.tb06664.x. PMID: 7077336
28. Human brain distribution of neurotensin in normals, schizophrenics, and Huntington’s choreics.  Manberg PJ, Nemeroff CB, Iversen LL, Rosser MN, Kizer JS, Prange AJ Jr. Ann N Y Acad Sci. 1982;400:354-67. doi: 10.1111/j.1749-6632.1982.tb31581.x. PMID: 6220630 No abstract available.
29. Neurotensin-induced hypothermia: evidence for an interaction with dopaminergic systems and the hypothalamic–pituitary–thyroid axis.  Nemeroff CB, Bissette G, Manberg PJ, Osbahr AJ 3rd, Breese GR, Prange AJ Jr. Brain Res. 1980 Aug 11;195(1):69-84. doi: 10.1016/0006-8993(80)90867-7. PMID: 6446951
30. Neurotensin: distribution of hypothermic response in mammalian and submammalian vertebrates.  Prange AJ Jr, Nemeroff CB, Bissette G, Manberg PJ, Osbahr AJ 3rd, Burnett GB, Loosen PT, Kraemer GW. Pharmacol Biochem Behav. 1979 Nov;11(5):473-7. doi: 10.1016/0091-3057(79)90027-3. PMID: 119233 No abstract available.
31. Alterations in nociception and body temperature after intracisternal administration of neurotensin, beta-endorphin, other endogenous peptides, and morphine.  Nemeroff CB, Osbahr AJ 3rd, Manberg PJ, Ervin GN, Prange AJ Jr. Proc Natl Acad Sci U S A. 1979 Oct;76(10):5368-71. doi: 10.1073/pnas.76.10.5368. PMID: 291952 Free PMC article.
32. Centrally administered neurotensin: activity in the Julou-Courvoisier muscle relaxation test in mice.  Osbahr AJ 3rd, Nemeroff CB, Manberg PJ, Prange AJ Jr. Eur J Pharmacol. 1979 Mar 1;54(3):299-302. doi: 10.1016/0014-2999(79)90090-6. PMID: 107032
33. Thyrotropin-releasing hormone and amphetamine: a comparison of pharmacological profiles in animals.  Manberg PJ, Nemeroff CB, Prange AJ Jr. Prog Neuropsychopharmacol. 1979;3(4):303-14. doi: 10.1016/0364-7722(79)90042-0. PMID: 122589 Review.
34. Neurotensin, a biologically active peptide.  Bissette G, Manberg P, Nemeroff CB, Prange AJ Jr. Life Sci. 1978 Nov 27;23(22):2173-82. doi: 10.1016/0024-3205(78)90201-1. PMID: 364232 Review. No abstract available.
35. Pharmaco-behavioral effects of hypothalamic peptides in animals and man: focus on thyrotropin-releasing hormone and neurotensin.  Nemeroff CB, Loosen PT, Bissette G, Manberg PJ, Wilson IC, Lipton MA, Prange AJ Jr. Psychoneuroendocrinology. 1978 Oct;3(3-4):279-310. doi: 10.1016/0306-4530(78)90019-7. PMID: 34843 Review. No abstract available.